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About 10 million Texans have diabetes or pre-diabetes (about the same number that are obese)

Moreover, investigators actively study visceral adiposity reduction, lipid metabolism, and body composition changes under controlled laboratory conditions

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These effects appear to be mediated, at least in part, through the GLP-1/Sirtuin (SIRT1) pathway or via suppression of myostatin, while concomitantly reducing inflammation, thereby mitigating muscle wasting associated with SO [92,93,94]